Over View Diabetes mellitus is mostly common endocrine disorder The charateristic is by impairment of glucosa metabolism There are two type of DM, type 1 and type 2 Type 1 is required insulin for treatment because of destruction of insulin-producing beta cells of the pancreas Type 2 may be managed by involving oral drugs, diet and sometime insulin; type 2 because lack of sufficient insulin production, mostly this is call "Insulin resistance" Diabetis mellitus can lead microvascular and macrovasvular complications, and large risk of cardiovascular disease Microvascular complication included nephropathy, peripheral neuropathy and retinopathy Macrovascular complications included peripheral vascular disease, cardiovacular disease such as stroke and myocardial infraction Microvascular and Macrovascular change production of diabetic foot ulcers (Nadia;163) Epidemiology Diabetes is most commonly occuring endorine disease, 2.3 million in U...